Depo shot side effects long term - So I have been on depo for about two years now and have never had severe problems. I have noticed since starting Depo that I have more vaginal discharge, more acne, and my boobs tend to be sore more often. However, this past week I have noticed an intense increase in some side effects. My boobs are extremely sore and I am having a mixture of ...

 
Other long-term birth control options include the: ... The Depo-Provera shot needs to be administered every three months. The birth control implant works for three years. ... Side effects usually .... Motorola apx cps r20 download

This article highlights medroxyprogesterone as it is used as contraception to prevent pregnancy. This activity discusses the mechanism of action, adverse effects, monitoring, and contraindications for medroxyprogesterone. Also, it highlights the important role that providers play in administering medroxyprogesterone and regularly monitoring patients for side effects.Potential side effects of cortisone shots increase with larger doses and repeated use. Side effects can include: Cartilage damage. Death of nearby bone. Joint infection. Nerve damage. Temporary facial flushing. Temporary flare of pain and inflammation in the joint. Temporary increase in blood sugar.After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. Effects on baby A small amount of the synthetic hormones in contraceptives will enter your milk, there is no evidence that this is dangerous to your baby. Some babies younger than six weeks may have difficulty metabolising the hormones and for this reason it is not recommended to start using a hormonal contraceptive until your baby is older.Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction.Apr 25, 2023 · When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ... Jan 6, 2022 · Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest. unexpected or excess milk flow from the breasts.Nov 24, 2017 · LousArk 24 Nov 2017. The Manufacturer recommends that you not use Depo Provera long term (more than 2 years), unless you have no option. In that case, you need to take the recommended breaks every couple of years. They state that it can take up to 18 months from the point you miss your shot, for your fertility to return. Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone.Rated Depo-Provera for Endometriosis Report . I was always happy and outgoing. Always with friends or making new friends to hang with. After almost 2 years on this drug I am: • Severely depressed • crazy anxiety • antisocial ( I try but I don’t ever want to be with people or do anything the more I get this shot ) • I don’t feel attracted to anyone • I cry everyday at least 5 ...A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics. The medication used in depot injections is the same as other forms of the drug, such as tablets or liquid. Apr 25, 2023 · When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ... Medroxyprogesterone acetate. Medroxyprogesterone acetate ( MPA ), also known as depot medroxyprogesterone acetate ( DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [9] [3] It is used as a method of birth control and as a part of menopausal hormone therapy.A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics. The medication used in depot injections is the same as other forms of the drug, such as tablets or liquid. Examples include birth control pills, as well as the vaginal ring (NuvaRing), skin patch (Xulane) and contraceptive injection (Depo-Provera). These are considered short-acting methods because you have to remember to use them on a daily, weekly or monthly basis. Long-acting hormonal methods.Many negative side effects usually go away after 2-3 months, once your body gets used to the shot. You can use our birth control app to keep track of the side effects you may be having. Most people on the shot have some change in their periods, including bleeding more days than usual, spotting between periods, or no periods. Mar 5, 2023 · severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest. Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone.Satisfaction. I'm a 40 yr. old that has been taking Depo-Provera for about 11 years. I like it all except, that I have to go to the doctor every 3 months and I do have the shakes and anxiety, heart palpitations, etc. BUT I also had anxiety before so not exactly sure if the shot is causing it. Also I do feel tired alot.Mar 3, 2023 · Similar side effects of the pill vs. Depo-Provera injection. Both methods can cause tenderness or soreness in the breasts. Other side effects of oral contraceptives and the Depo-Provera shot include headaches and mood changes. Both methods can lead to a decreased interest in sex ( decreased libido) in some women. Good advice below - re: leaving your ovaries in! I had my one and only grand mal seizure on the day I got my period back - about 6 months after taking my last Depo Provera shot. I only took 2 injections of the drug but stopped it due to concerns about loss of bone density and the strange periods that I was having. Olanzapine as pamoate monohydrate is a long-acting injectable or depot form of olanzapine and provides another option for maintenance treatment of schizophrenia. As with oral olanzapine, weight gain and metabolic effects (raised serum cholesterol, triglyceride and glucose levels) are common. Establish tolerability and response to oral ...Dec 7, 2022 · pounding in the ears. pressure in the stomach. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. seizures. sensation of spinning. severe or continuing stomach pain. slow growth in children. slow or fast heartbeat. sores, ulcers, or white spots on the lips or tongue or inside the mouth. May 2, 2023 · Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Depression or other mood changes. Eyesight changes or loss, bulging eyes, or change in how contact lenses feel. A lump in the breast, breast pain or soreness, or nipple discharge. Flu -like signs. After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding.Depo-Provera Contraceptive Injection should not be used as a long-term birth control method (i.e., longer than 2 years) unless other birth control methods are considered inadequate. (See Warnings and Precautions (5.1)). 1 INDICATIONS AND USAGE Depo-Provera CI is indicated only for the prevention of pregnancy. The loss of bone mineral density Risks. Abdominal pain. Bloating. Decreased interest in sex. Depression. Dizziness. Headaches. Irregular periods and breakthrough bleeding. Nervousness. Weakness and fatigue. Weight gain.In many cases, unwanted effects of the Mirena IUD are not long-term. According to Planned Parenthood, common side effects such as spotting between periods and cramping typically get better in 3 ...After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding.Many negative side effects usually go away after 2-3 months, once your body gets used to the shot. You can use our birth control app to keep track of the side effects you may be having. Most people on the shot have some change in their periods, including bleeding more days than usual, spotting between periods, or no periods. signs of a blood clot - sudden numbness or weakness, severe headache, chest pain, sudden cough, coughing up blood; problems with vision or speech, swelling or pain in an arm or leg. Common Depo-Provera side effects may include: changes in your menstrual periods; weakness, feeling tired; stomach pain; feeling nervous;Jun 16, 2021 · To go off of this form of birth control, just don’t get your next shot. But be aware that your periods and fertility may take more than the initial three months to return. “In some people, it ... Jul 15, 2023 · Warning: Blood Pressure IncreasesTestosterone undecanoate can cause blood pressure (BP) increases that can increase the risk of major adverse cardiovascular events (MACE), including non-fatal myocardial infarction, non-fatal stroke and cardiovascular death. You might notice: Uneven menstrual periods or no periods at all Headaches Nervousness Depression Dizziness Acne Changes in appetite Weight gain Unwanted facial and body hair Hair loss Loss of bone mineral density Belly pain Bloating Breakthrough bleeding Fatigue Less interest in sex Weakness ... Nov 12, 2020 · This article highlights medroxyprogesterone as it is used as contraception to prevent pregnancy. This activity discusses the mechanism of action, adverse effects, monitoring, and contraindications for medroxyprogesterone. Also, it highlights the important role that providers play in administering medroxyprogesterone and regularly monitoring patients for side effects. Effects on baby A small amount of the synthetic hormones in contraceptives will enter your milk, there is no evidence that this is dangerous to your baby. Some babies younger than six weeks may have difficulty metabolising the hormones and for this reason it is not recommended to start using a hormonal contraceptive until your baby is older. Forty-three subjects (37% of discontinuers) restarted Depo-Provera during the study period, with a mean time to restart of 8.4 months after the last Depo-Provera injection. Side effects were the main reported reason for Depo-Provera discontinuation, primarily menstrual irregularities (26%) and weight gain (18%).Nov 5, 2022 · 9 Common Depo-Provera Side Effects Irregular Menstrual Bleeding. Menstrual cycle changes are the most common side effects of the Depo-Provera shot. Many... No Periods. After a few shots, Depo-Provera may stop menstruation altogether in some people. Others may have very light... Anxiety and Mood ... Lupron is a drug doctors prescribe to treat prostate cancer. It works by reducing testosterone levels in the body, slowing cancer growth. Lupron is the brand name for leuprolide acetate. Lupron ...Nov 24, 2017 · LousArk 24 Nov 2017. The Manufacturer recommends that you not use Depo Provera long term (more than 2 years), unless you have no option. In that case, you need to take the recommended breaks every couple of years. They state that it can take up to 18 months from the point you miss your shot, for your fertility to return. Depo-Provera Contraceptive Injection should not be used as a long-term birth control method (i.e., longer than 2 years) unless other birth control methods are considered inadequate. (See Warnings and Precautions (5.1)). 1 INDICATIONS AND USAGE Depo-Provera CI is indicated only for the prevention of pregnancy. The loss of bone mineral densityDepo Medrol 80 MG Injection is used for treating Gout which is a type of joint inflammation. Sudden pain at night time and redness of the joints are few symptoms of Gout. Psoriasis. Depo Medrol 80 MG Injection is used to cure Psoriasis which is a type of skin disease. Itchy or sore patches and red skin are few symptoms of Psoriasis.Jun 14, 2023 · DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in three strengths: 20 mg/mL, 40 mg/mL, 80 mg/mL. Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ...Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone.Jan 6, 2022 · Allergy shots are a form of treatment called immunotherapy. Each allergy shot contains a tiny amount of the specific substance or substances that trigger your allergic reactions. These are called allergens. Allergy shots contain just enough allergens to stimulate your immune system — but not enough to cause a full-blown allergic reaction. some people may put on weight when they use Depo-Provera or Sayana Press contraceptive injections; you may experience side effects like headaches, acne, hair loss, decreased sex drive and mood swings; any side effects can continue for as long as the injection lasts (8 or 13 weeks) and for some time after; Risks May 15, 2002 · In fact, women frequently discontinue hormonal contraception because of irregular bleeding and other side effects. 1 – 3 One study 4 found that 32 percent of 1,657 women who started taking oral ... Medical side effects: The results of two major world studies have shown that women who take Depo-Provera for two years or more before age 25 have at least a 190% increased risk of developing ...Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. It is similar to but slightly more potent than prednisone / prednisolone.Depo-Provera Vial Contraceptives. - Uses, Side Effects, This medication may cause serious bone loss which may not return to normal after you stop using it. The risk of bone loss increases with ... Nov 5, 2022 · 9 Common Depo-Provera Side Effects Irregular Menstrual Bleeding. Menstrual cycle changes are the most common side effects of the Depo-Provera shot. Many... No Periods. After a few shots, Depo-Provera may stop menstruation altogether in some people. Others may have very light... Anxiety and Mood ... Loss of bone density, if Lupron Depot is taken long term. Convulsions (violent shaking, seizures). Problems with your heart’s electrical activity, such as long QT syndrome .Common side effects of Depo-Estradiol may include: breast pain; headache; vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding; thinning scalp hair; or. nausea, vomiting, bloating, stomach cramps. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side ...headaches and migraine. hot flashes/night sweats. nausea and vomiting. pain. vaginitis. weight gain. People taking Lupron develop symptoms that are similar to menopause, including hot flashes ...Common side effects may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach ...Long-term side effects of birth control pills do occur, but using oral contraceptives generally is considered safe and effective for most people. In some cases, pills that contain estrogen can raise the risk of stroke, blood clots, and heart attacks in some people and should be avoided. For many people, the benefits of using birth control long ...Depo-Provera is an injection that prevents pregnancy for 3 months at a time. It contains a synthetic hormone called progestin. The birth control shot works similarly to the pill by preventing ...Appropriate Use. The Depo-Provera birth control shot has advantages and disadvantages compared to other types of birth control. While it's convenient and effective, for example, the Depo shot also carries the risk of side effects like irregular bleeding and bone loss. This article looks at some of the pros and cons of using Depo-Provera.Common side effects of Depo-Medrol may include: weight gain (especially in your face or your upper back and torso); slow wound healing; muscle pain or weakness; thinning skin, increased sweating; stomach discomfort, bloating; headache; or. changes in your menstrual periods. This is not a complete list of side effects and others may occur.headaches and migraine. hot flashes/night sweats. nausea and vomiting. pain. vaginitis. weight gain. People taking Lupron develop symptoms that are similar to menopause, including hot flashes ...Aug 1, 2023 · lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients. For most people, being on birth control long term is safe. Birth control can lower your risk for some cancers and raise your risk for others. It can cause blood clots, heart attacks, and strokes — but the risks are small. Being on birth control doesn’t make it harder to become pregnant once you stop it. 02:48.Jul 1, 2021 · There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ... Dec 14, 2001 · Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ... Mar 6, 2023 · Lupron is a drug doctors prescribe to treat prostate cancer. It works by reducing testosterone levels in the body, slowing cancer growth. Lupron is the brand name for leuprolide acetate. Lupron ... Common side effects of Depo-Estradiol may include: breast pain; headache; vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding; thinning scalp hair; or. nausea, vomiting, bloating, stomach cramps. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side ...Jan 11, 2023 · Appropriate Use. The Depo-Provera birth control shot has advantages and disadvantages compared to other types of birth control. While it's convenient and effective, for example, the Depo shot also carries the risk of side effects like irregular bleeding and bone loss. This article looks at some of the pros and cons of using Depo-Provera. lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients.Purpose and method: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women ...Depo-Provera use may also delay the return of your fertility. About 50% of women will be able to get pregnant within 10 months after their last Depo-Provera injection, but it can take up to 18 months for fertility to return. Some women report irregular or continuous bleeding when using Depo-Provera along with other unwanted side effects.Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ...Mar 17, 2022 · Depo-Provera is an injection that prevents pregnancy for 3 months at a time. It contains a synthetic hormone called progestin. The birth control shot works similarly to the pill by preventing ... lightening of normal skin color. pain, redness, or hard skin at the injection site. pitting or depression of the skin at the injection site. red face. reddish purple lines on the arms, face, legs, trunk, or groin. swelling of the stomach area. thinning of the scalp hair. Other side effects not listed may also occur in some patients.The most common side effects associated with DMPA use are bothersome but benign and typically improve with time or upon discontinuation, including irregular bleeding, weight gain, dizziness, abdominal pain, and anxiety . Occasionally, other side effects do occur and may cause significant distress to the patient.Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ...Summary. Commonly reported side effects of paliperidone include: akathisia, tachycardia, and drowsiness. Other side effects include: basal ganglia disease, dyskinesia, dystonia, orthostatic hypotension, postencephalitic parkinson's disease, sialorrhea, and prolonged qt interval on ecg. Continue reading for a comprehensive list of adverse effects.

After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. . Bengtson

depo shot side effects long term

Mar 6, 2013 · The most common side effects associated with DMPA use are bothersome but benign and typically improve with time or upon discontinuation, including irregular bleeding, weight gain, dizziness, abdominal pain, and anxiety . Occasionally, other side effects do occur and may cause significant distress to the patient. Purpose and method: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women ...Hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal ... Apr 25, 2023 · When To See a Healthcare Provider. Signs of pregnancy after Depo-Provera ( medroxyprogesterone ) may include missed period, nausea, breast tenderness, and more. Many people are able to get pregnant around 8 to 10 months after their last Depo-Provera shot. Depo-Provera, an injectable birth control method, is more than 99% effective at preventing ... Mar 5, 2023 · severe, sudden headache. shortness of breath. slurred speech. stopping of menstrual bleeding. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sudden, unexplained shortness of breath. swelling of the fingers, hands, feet, or lower legs. troubled breathing at rest. Pros No need to take a daily pill. You’ll get a shot once every 12 to 13 weeks. Less opportunity to miss a dose. It’s very common to occasionally miss a daily pill. With a shot, you won’t have...Dec 14, 2001 · Campbell complains about serious side effects from Depo-Provera herself, so those attracted to her survey undoubtedly tend to have worries about the drug. The number one complaint was weight gain ... It gives long-term protection as long as you get the shot every 3 months. It's very effective. You get birth control without having to take estrogen. It can make your period lighter and...Limiting contraceptive options like DMPA may disproportionately affect adolescents and disadvantaged women. Depot medroxyprogesterone acetate inhibits the secretion of pituitary gonadotropins, resulting in anovulation and decreased production of estrogen. Decreased estrogen production is of concern because it is associated with a decrease in ...A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics. The medication used in depot injections is the same as other forms of the drug, such as tablets or liquid. You might notice: Uneven menstrual periods or no periods at all Headaches Nervousness Depression Dizziness Acne Changes in appetite Weight gain Unwanted facial and body hair Hair loss Loss of bone mineral density Belly pain Bloating Breakthrough bleeding Fatigue Less interest in sex Weakness ... There should be confidence in that." “The long-term side effects of COVID infection are a major concern. Up to 10 percent of people who have COVID experience side effects” such as difficulty thinking, pain, tiredness, loss of taste and depression. “We don’t know why that is, how long these symptoms will last or if there are effective ...Aug 9, 2023 · Depo-Provera use may also delay the return of your fertility. About 50% of women will be able to get pregnant within 10 months after their last Depo-Provera injection, but it can take up to 18 months for fertility to return. Some women report irregular or continuous bleeding when using Depo-Provera along with other unwanted side effects. Many negative side effects usually go away after 2-3 months, once your body gets used to the shot. You can use our birth control app to keep track of the side effects you may be having. Most people on the shot have some change in their periods, including bleeding more days than usual, spotting between periods, or no periods. The birth control shot (sometimes called Depo-Provera, the Depo shot, or DMPA) contains the hormone progestin. Progestin stops you from getting pregnant by preventing ovulation. When there’s no egg in the tube, pregnancy can’t happen. It also works by making cervical mucus thicker. When the mucus on the cervix is thicker, the sperm can’t ...Aug 7, 2023 · signs of a blood clot - sudden numbness or weakness, severe headache, chest pain, sudden cough, coughing up blood; problems with vision or speech, swelling or pain in an arm or leg. Common Depo-Provera side effects may include: changes in your menstrual periods; weakness, feeling tired; stomach pain; feeling nervous; Jun 14, 2023 · DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue, or intralesional injection. It is available in three strengths: 20 mg/mL, 40 mg/mL, 80 mg/mL. Sodium Chloride was added to adjust tonicity. When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. .

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